Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687598 | 0.90 | KMT2A (0.53) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| Bromide SCHEMBL10687727 | 0.89 | KMT2A (0.52) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10692550 | 0.89 | KMT2A (0.52) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| Phosphoric Acid SCHEMBL10684644 | 0.89 | NPC1 (0.54) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| Phosphoric Acid SCHEMBL10788725 | 0.88 | KMT2A (0.49) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| SCHEMBL10685997 | 0.88 | KMT2A (0.54) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| SCHEMBL10687023 | 0.87 | KMT2A (0.45) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| SCHEMBL10688189 | 0.87 | ACHE (0.56) | KMT2AMAPTMEN1POLBHPGD | |
| Phosphoric Acid SCHEMBL10681481 | 0.87 | KMT2A (0.51) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 | |
| SCHEMBL10689917 | 0.87 | NPC1 (0.50) | NPC1RAB9ACYP2C9NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769384-A | ANTIULCER AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1988-09-06 | — | — | US | disclosed |