Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012268 | 0.94 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL10012856 | 0.92 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL10012791 | 0.89 | TDP1 (0.39) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4676717 | 0.86 | TSHR (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4676714 | 0.86 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL10011389 | 0.85 | TDP1 (0.39) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL19105479 | 0.84 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL30104631 | 0.84 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL630320 | 0.84 | TSHR (0.47) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL6993751 | 0.84 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737538-A | THERMOSETTING ACETYLENE TERMINATED POLYAMIDE, UNSATURATED CROSSLINKER, FILLER, FREE RADICAL INITIATOR, BUTADIENE-STYRENE BLOCK POLYMER | SHELL OIL COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0217435-A2 | Polymer concrete compositions and process for the preparation thereof | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-08 | — | — | EP | disclosed |
| EP-0097383-B1 | POLYESTER MOULDING COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-01 | — | — | EP | disclosed |
| EP-0097383-A2 | Polyester moulding compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-04 | — | — | EP | disclosed |
| US-4400478-A | Molding compounds comprising a mixture of block copolymers employed as a modifier for thermosetting unsaturated polyester resin compositions | SHELL OIL COMPANY (US) | 1983-08-23 | — | — | US | disclosed |