SCHEMBL630320

SCHEMBL630320

C=CCOC(=O)C(C)OC(=O)C=C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.47
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 1/20 0.37
MAPT P10636 2/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 5/20 0.36
CYP3A4 P08684 4/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4673003 0.87 TDP1 (0.40) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL21631296 0.87 TDP1 (0.40) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL10687652 0.84 TDP1 (0.43) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL14586207 0.84 TSHR (0.50) TSHRTDP1HPGDALDH1A1CYP3A4
SCHEMBL9562348 0.84 TSHR (0.43) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1655986 0.82 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL4676717 0.82 TSHR (0.44) TSHRTDP1HPGDMAPTCACNA1B
SCHEMBL4676714 0.82 TDP1 (0.42) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL10012268 0.82 TDP1 (0.42) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL6993751 0.81 TDP1 (0.41) TSHRTDP1HPGDMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3474952-B1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM & HAAS (US) 2021-07-28 EP claimed
US-10507174-B2 Skin care compositions ROHM AND HAAS COMPANY (US) 2019-12-17 US claimed
CN-105683229-B Polyolefin/(methyl) acrylic acid impact modifying agent and preparation method 陶氏环球技术有限责任公司 2019-09-27 CN claimed
US-20190133913-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM & HAAS (US) 2019-05-09 US claimed
EP-3474952-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS Rohm and Haas Company (US) 2019-05-01 EP claimed
CN-109310890-A Composition containing latex particle and UV absorbent 罗门哈斯公司 2019-02-05 CN claimed
WO-2017222570-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND UV ABSORBERS ROHM AND HAAS COMPANY (US) 2017-12-28 WO claimed
CN-104098888-B Containing the aqueous pu dispersions of oligomer, the preparation of ethylene monomer copolymer/polyurethane hybrid polymer beads and application 万华化学(广东)有限公司 2016-08-31 CN claimed
EP-2632981-B1 A THERMOPLASTIC COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM ROHM & HAAS (US) 2015-03-18 EP claimed
CN-104098888-A Preparation and application for water-based polyurethane dispersoid containing oligomer and vinyl monomer copolymer/polyurethane hybridization polymer granular WANHUA CHEMICAL GUANGDONG CO LTD 2014-10-15 CN claimed
US-20130237673-A1 Thermoplastic Composition, Method of Producing the Same, and Articles Made Therefrom ROHM AD HAAS COMPANY (US) 2013-09-12 US claimed
EP-2632981-A1 A THERMOPLASTIC COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM Rohm and Haas Company (US) 2013-09-04 EP claimed
WO-2012058256-A1 A THERMOPLASTIC COMPOSITION, METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM ROHM AND HAAS COMPANY (US) 2012-05-03 WO claimed
US-12071536-B2 Bimodal silicone-acrylic polymer particles ROHM AND HAAS COMPANY (US) 2024-08-27 US disclosed
US-12043685-B2 Polymerizing silicone and acrylic monomers DOW SILICONES CORPORATION (US) 2024-07-23 US disclosed
US-11981804-B2 Modified styrene-acrylonitrile ROHM AND HAAS COMPANY (US) 2024-05-14 US disclosed
US-5187309-A Catalytic reaction of acrylic acid and lower alkanol, azeoltropic distillation ELF ATOCHEM S.A. (FR) 1993-02-16 US disclosed
EP-0269324-B1 PARTICULATE POLYMER COMPOSITION, A METHOD OF MAKING PARTICULATE POLYMER COMPOSITIONS, AND LIGHT-SCATTERING THERMOPLASTIC POLYMER COMPOSITIONS CONTAINING THE PARTICULATE POLYMERS ROHM AND HAAS COMPANY (US) 1992-12-30 EP disclosed
EP-0342283-A1 Thermoplastic and thermoset polymer compositions ROHM AND HAAS COMPANY (US) 1989-11-23 EP disclosed
EP-0269324-A2 Particulate polymer composition, a method of making particulate polymer compositions, and light-scattering thermoplastic polymer compositions containing the particulate polymers ROHM AND HAAS COMPANY (US) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10507174-B2 Skin care compositions CUTA, MMS19, SOD1 TSHR 4594/4885TDP1 1096/4885HPGD 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.