Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410732 | 0.82 | TSHR (1.00) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL39591 | 0.82 | TSHR (1.00) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL28129133 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL30953679 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Water SCHEMBL27781603 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL4372377 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL2790297 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Iodide SCHEMBL31305312 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Water SCHEMBL7109306 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Water SCHEMBL27580150 | 0.80 | TSHR (0.95) | TSHRMAPK1HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723986-A | Herbicidal oxazolidines and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |