Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710496 | 0.88 | KMT2A (0.47) | KMT2APOLQCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9821906 | 0.87 | CYP1A2 (0.60) | KMT2ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL10689404 | 0.85 | SMN1; SMN2 (0.48) | KMT2APOLQCYP1A2CYP2C19LIPE | |
| SCHEMBL7934892 | 0.82 | KMT2A (0.50) | KMT2AABCB11ALDH1A1PPARG | |
| SCHEMBL11357447 | 0.81 | HPGD (0.60) | KMT2ACYP3A4CYP2C19HPGDLIPE | |
| SCHEMBL9325794 | 0.79 | HPGD (0.47) | KMT2APOLQCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9571201 | 0.79 | HPGD (0.47) | KMT2APOLQCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11007973 | 0.78 | KMT2A (0.48) | KMT2AABCB11HPGDPTGDR2PPARG | |
| SCHEMBL10692045 | 0.77 | CYP1A2 (0.62) | KMT2ACYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL10675473 | 0.76 | KMT2A (0.55) | KMT2ACYP1A2CYP2C19ABCB11PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753673-A | GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4628099-A | INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4551170-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-11-05 | — | — | US | disclosed |
| US-4523017-A | REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND | THE DOW CHEMICAL COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4491468-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4479001-A | Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1984-10-23 | — | — | US | disclosed |