Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30783187 | 0.87 | DHODH (0.42) | KMT2AP2RY1PPARGNFE2L2FPR2 | |
| SCHEMBL8574571 | 0.85 | SCN9A (0.49) | FPR2SCN9AALDH1A1MAPTATM | |
| SCHEMBL9173964 | 0.83 | KMT2A (0.54) | KMT2AP2RY1PPARGHTR1ASLC6A2 | |
| SCHEMBL10689409 | 0.82 | KMT2A (0.47) | KMT2APPARGABCB11ALDH1A1 | |
| SCHEMBL9780575 | 0.81 | PPARG (0.60) | KMT2APPARGABCB11ADRA2AADRA2B | |
| SCHEMBL9780582 | 0.81 | PPARG (0.60) | KMT2APPARGABCB11ADRA2AADRA2B | |
| SCHEMBL9482952 | 0.81 | KMT2A (0.54) | KMT2AP2RY1SLC6A2ALDH1A1 | |
| SCHEMBL11034685 | 0.81 | KMT2A (0.54) | KMT2AP2RY1SLC6A2ALDH1A1MAPT | |
| SCHEMBL10675473 | 0.76 | KMT2A (0.55) | KMT2APPARGABCB11 | |
| SCHEMBL1967959 | 0.76 | KMT2A (0.58) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291400-B1 | Herbicidal compounds | ZENECA LIMITED (GB) | 2001-09-18 | — | — | US | disclosed |
| US-5958839-A | HERBICIDALLY ACTIVE SUBSTITUTED CYCLIC DIONES | ZENECA LITMITED (GB) | 1999-09-28 | — | — | US | disclosed |
| EP-0283261-B2 | Herbicidal substituted cyclic diones | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5563115-A | PRE- AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5426091-A | Herbicidal compounds | ZENECA LIMITED (GB) | 1995-06-20 | — | — | US | disclosed |
| US-5250501-A | Herbicidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-05 | — | — | US | disclosed |
| US-5210312-A | Preparing herbicidal tetraalkyl cyclohexan-1,3,5-triones from unalkylated benzenetriols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0248554-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-03 | — | — | EP | disclosed |
| US-5098464-A | Preemergence or postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0266068-B1 | HERBICIDAL COMPOSITION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-26 | — | — | EP | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |
| US-4975113-A | Herbeicidal composition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-04 | — | — | US | disclosed |
| US-4912262-A | Reacting a cyclohexane-1,3,5-trione compound with a acylnitrile in presence of a base and Lewis acid | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-27 | — | — | US | disclosed |
| EP-0283261-A2 | Herbicidal substituted cyclic diones | ZENECA LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |
| EP-0283152-A2 | Process for the preparation of substituted cyclohexane-1,3,5-triones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-21 | — | — | EP | disclosed |
| EP-0266068-A1 | Herbicidal composition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-04 | — | — | EP | disclosed |
| EP-0248554-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-09 | — | — | EP | disclosed |
| EP-0234674-A1 | Herbicidal composition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-02 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |
| EP-0229034-A2 | Hexopyranoses and compositions for agricultural use | HER MAJESTY THE QUEEN in right of New Zealand Department of Scientific and Industrial Research (NZ) | 1987-07-15 | — | — | EP | disclosed |