Thiourea

Thiourea

SCHEMBL1068944

C=C(CO)CO.NC(N)=S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ATM Q13315 1/20 0.43
ATR Q13535 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL11647233 0.88 TSHR (0.33) TSHRATMATR
SCHEMBL229980 0.80
Urea SCHEMBL133649 0.79 TDP1 (0.43) TSHR
Ammonia Solution, Strong SCHEMBL6471729 0.76
Thiourea SCHEMBL10777311 0.71
SCHEMBL3610599 0.68
SCHEMBL1512939 0.68
Thiourea SCHEMBL20912597 0.68
Thiourea SCHEMBL28113885 0.68
SCHEMBL21889222 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925366-A PERMEATION/BINDING AGENT, THIO CROSSLINKING AGENT, AND CHELATE COMPOUND REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-07-20 US claimed
US-5785959-A MIXTURE CONTAINING A PERMEATION/BINDING AGENT, A THIO CROSSLINKING AGENT, A CHELATING AGENT, WATER AND AN OIL REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-07-28 US claimed
WO-1998006376-A1 NAIL STRENGTHENING COMPOSITIONS AND A METHOD FOR STRENGTHENING NAILS REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-02-19 WO claimed
US-4612188-A CHANGE \"OXIDATION DYES\" TO \"OXIDATION COLOR DYES\" 15 024 4612 188 L'OREAL (FR) 1986-09-16 US claimed
US-4547363-A FIRST LIQUID COMPONENT CONTAINING DIMETHYLOL ETHYLENE THEOPHYLLINESTABILIZER AND SOLVENTS; SECOND CONTAINING CATALYST AND AMINOACETICACID JOOS BERNHARD (CH) 1985-10-15 US claimed
EP-0068369-B1 NAIL PROTECTING PREPARATIONS FOR STRENGTHENING, PARTICULARLY HARDENING LIVING NAILS Joos, Dr. Bernhard (CH) 1985-09-25 EP claimed
US-4172887-A Hair conditioning compositions containing crosslinked polyaminopolyamides L'OREAL (FR) 1979-10-30 US claimed
US-20240044063-A1 ECO-FRIENDLY FLAME RETARDANT FABRIC AND PREPARATION METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHANGWON NATIONAL UNIVERSITY (KR) 2024-02-08 US disclosed
US-11207263-B2 Cosmetic compositions DOW SILICONES CORPORATION (US) 2021-12-28 US disclosed
EP-3771335-A1 REPELLENT COMPOSITION Athenion AG (CH) 2021-02-03 EP disclosed
EP-3771336-A1 REPELLENT COMPOSITION Athenion AG (CH) 2021-02-03 EP disclosed
US-20200237639-A1 COSMETIC COMPOSITIONS DOW SILICONES CORP (US) 2020-07-30 US disclosed
WO-2019045830-A1 COSMETIC COMPOSITIONS DOW SILICONES CORPORATION (US) 2019-03-07 WO disclosed
US-4411884-A Cosmetic agents based on polycationic polymers, and their use in cosmetic compositions SOCIETE ANONYME DITE: L'OREAL (FR) 1983-10-25 US disclosed
US-4381919-A POLYAMINES SOCIETE ANONYME DITE: L'OREAL (FR) 1983-05-03 US disclosed
US-4381294-A Process for reinforcing fragile or brittle nails and a composition containing a cationic polymer for use in said process SOCIETE ANONYME DITE: L'OREAL (FR) 1983-04-26 US disclosed
US-4197865-A Treating hair with quaternized polymers L'OREAL (FR) 1980-04-15 US disclosed
US-4172887-A Hair conditioning compositions containing crosslinked polyaminopolyamides L'OREAL (FR) 1979-10-30 US disclosed
US-4115364-A MELT SPINNING WITH A THERMOPLASTIC NYLON, CURING, REACTING WITH UREA COMPOUND NIPPON KYNOL INCORPORATED (JP) 1978-09-19 US disclosed
US-4076540-A IONIC COMPLEX, BORIC ACID COMPOUND, UREA STOSSEL ERNEST 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200237639-A1 COSMETIC COMPOSITIONS H1-0, H1-3, HRH3 TSHR 625/4885ATM 2926/4885ATR 3211/4885
US-11207263-B2 Cosmetic compositions H1-0, H1-3, HRH3 TSHR 492/4885ATM 3078/4885ATR 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.