Urea

Urea

SCHEMBL133649

C=C(CO)CO.NC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
OR51E2 Q9H255 2/20 0.43
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229980 0.80
Urea SCHEMBL5081616 0.79
Thiourea SCHEMBL1068944 0.79 TSHR (0.43) TSHR
Ammonia Solution, Strong SCHEMBL6471729 0.76
Acetic Acid SCHEMBL9703708 0.76 FFAR3 (0.47) TDP1ALDH1A1LMNAOR51E2TSHR
SCHEMBL25805 0.76
Acetic Acid SCHEMBL11713527 0.76 FFAR3 (0.47) TDP1ALDH1A1LMNAOR51E2TSHR
SCHEMBL27930728 0.76 TDP1 (0.42) TDP1ALDH1A1LMNAOR51E2TSHR
Fluoride SCHEMBL30158789 0.73
Urea SCHEMBL3393016 0.73 TDP1 (0.38) TDP1ALDH1A1LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4332175-B1 OPTICAL BRIGHTENING AGENT COMPOSITION CHT Germany GmbH (DE) 2025-05-21 EP claimed
CN-119372852-A Anti-fibrillation finishing method and device for lyocell yarn 青岛大学 2025-01-28 CN claimed
CN-119352317-A Jig dyeing process for preventing fibrillation of lyocell woven fabric 北京中纺化工股份有限公司 2025-01-24 CN claimed
CN-118087276-A Water-absorbing quick-drying auxiliary agent, treatment method, fiber and fabric 联润翔(青岛)纺织科技有限公司 2024-05-28 CN claimed
EP-3307765-B1 RECOMBINANT PROTEIN FIBER YARNS WITH IMPROVED PROPERTIES BOLT THREADS INC (US) 2024-04-10 EP claimed
CN-114614010-B Lithium ion battery silicon-containing negative electrode slurry and preparation method and application thereof 万华化学(四川)有限公司 2024-04-09 CN claimed
WO-2024046735-A1 OPTICAL BRIGHTENING AGENT COMPOSITION CHT Germany GmbH (DE) 2024-03-07 WO claimed
EP-4332175-A1 OPTICAL BRIGHTENING AGENT COMPOSITION CHT Germany GmbH (DE) 2024-03-06 EP claimed
CN-115181468-B Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2024-03-05 CN claimed
CN-111374965-B Water-soluble coenzyme Q10 inclusion compound with high stability and preparation method thereof 上海融澈水性材料有限公司 2024-01-16 CN claimed
US-4438533-A FLOCK FIBERS WITH POLYMERIC BINDERS KUFNER TEXTILWERKE KG (DE) 1984-03-27 US claimed
US-4435442-A Method and apparatus for reinforcing face fabric materials for garments KUFNER TEXTILWERKE KG (DE) 1984-03-06 US claimed
EP-0092908-A2 Hydrophilic polymer composition for injection molding WARNER-LAMBERT COMPANY (US) 1983-11-02 EP claimed
US-4051215-A POLYESTERS, POLYETHERESTERS UNITIKA KABUSHIKI KAISHA (JA) 1977-09-27 US claimed
US-4032992-A Controlling degree of reaction by controlling heat input in cellulose textile-reactant systems J. P. STEVENS & CO., INC. (US) 1977-07-05 US claimed
US-4018959-A Corrugating adhesive compositions containing thermoplastic polymer, thermosetting resin, and starch NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1977-04-19 US claimed
US-3995999-A Process of imparting creasability of cellulosic and other hydroxy-containing polymeric fibers and fabrics by reaction of N-methylol derivatives in the presence of phosphorylating agents and products THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-12-07 US claimed
US-3984367-A UREAS, ALDEHYDES, AMINES, PHOSPHORIC ACID PEARSON, GLENN A. 1976-10-05 US claimed
US-3983269-A CONDENSATION PRODUCT OF ALDEHYDE, AMINE AND INORGANIC ACID REACTED WITH UREA PEARSON, GLENN A. 1976-09-28 US claimed
US-3933274-A Product for the treatment of cellulosic fabrics LEVER BROTHERS COMPANY (US) 1976-01-20 US claimed