SCHEMBL1068979

SCHEMBL1068979

c1ccc(NC2CCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
MAPT P10636 4/20 0.47
GAA P10253 4/20 0.47
LMNA P02545 4/20 0.47
POLB P06746 1/20 0.47
KDM4E B2RXH2 3/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
EPHX1 P07099 1/20 0.46
EPHX2 P34913 1/20 0.46
RAB9A P51151 1/20 0.46
NPY5R Q15761 1/20 0.44
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425186 0.95 KDM4E (0.52) CARM1PRMT6MAPTGAALMNA
SCHEMBL18639265 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL29594018 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL285479 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL24198978 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL24514268 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL1485904 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
Hydrochloric Acid SCHEMBL11683673 0.93 GAA (0.50) CARM1PRMT6MAPTGAALMNA
SCHEMBL10480342 0.93 KDM4E (0.53) CARM1PRMT6MAPTGAALMNA
SCHEMBL17822020 0.93 GAA (0.50) CARM1PRMT6MAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322132-B N-substituted indole compound and synthesis method thereof 陕西科技大学 2024-05-28 CN claimed
CN-115322132-A N-substituted indole compound and synthetic method thereof 陕西科技大学 2022-11-11 CN claimed
EP-2261203-B1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARING PROCESSES AND THE USES THEREOF BEIJING YINGU CENTURY PHARMACY CO LTD (CN) 2016-05-25 EP claimed
US-8673981-B2 Phenylcyclobutylamide derivatives and their stereoisomers, the preparation processes and uses thereof YinGu Pharmaceutical Co., Ltd (CN) 2014-03-18 US claimed
US-20130289124-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARATION PROCESSES AND USES THEREOF YinGu Pharmaceutical Co., Ltd (CN) 2013-10-31 US claimed
US-8497305-B2 Phenylcyclobutylamide derivatives and their stereoisomers, the preparation processes and uses thereof YinGu Pharmaceutical Co., Ltd (CN) 2013-07-30 US claimed
US-20110224305-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARATION PROCESSES AND USES THEREOF BEIJING YINGU CENTURY PHARMACY CO. LTD (CN) 2011-09-15 US claimed
EP-2318363-A1 HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS Nuevolution A/S (DK) 2011-05-11 EP claimed
EP-2261203-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARING PROCESSES AND THE USES THEREOF Beijing Cachet Biomedical Co., Ltd (CN) 2010-12-15 EP claimed
WO-2009152824-A1 HETEROCYCLIC DERIVATIVES AS IAP BINDING COMPOUNDS NUEVOLUTION A/S (DK) 2009-12-23 WO claimed
EP-4610285-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
EP-4610287-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
US-20250236723-A1 RESIN SHEET, LAMINATED BOARD, METAL-CLAD LAMINATED BOARD, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE RESONAC CORPORATION (JP) 2025-07-24 US disclosed
CN-120092029-A Resin composition, cured product, prepreg, metal foil-clad laminate, resin composite sheet, and printed wiring board 三菱瓦斯化学株式会社 2025-06-03 CN disclosed
CN-119899377-A Polymaleimide compound, curable composition, cured product, prepreg, circuit board, laminate film, semiconductor sealing material, and semiconductor device DIC株式会社 2025-04-29 CN disclosed
WO-2009124458-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARING PROCESSES AND THE USES THEREOF 北京嘉事堂生物医药有限公司 (CN) 2009-10-15 WO disclosed
EP-0900237-B1 PHOTOACTIVE COMPOUNDS FOR USE WITH NARROW WAVELENGTH BAND ULTRAVIOLET (UV) CURING SYSTEMS ALBEMARLE CORP (US) 2002-10-09 EP disclosed
US-6140385-A USING A LESSER AMOUNT OF PHOTOINITIATOR AND NO SYNERGIST WHEN PHOTOPOLYMERIZING AN UNSATURATED COMPOUND, E.G., (METH)ACRYLATE; IRRADIATION WITH ULTRAVIOLET LIGHT OF WAVELENGTH OF 200-450 NM OR VISIBLE LIGHT FIRST CHEMICAL CORPORATION (US) 2000-10-31 US disclosed
EP-0900237-A1 PHOTOACTIVE COMPOUNDS FOR USE WITH NARROW WAVELENGTH BAND ULTRAVIOLET (UV) CURING SYSTEMS First Chemical Corporation (US) 1999-03-10 EP disclosed
WO-1997044364-A1 PHOTOACTIVE COMPOUNDS FOR USE WITH NARROW WAVELENGTH BAND ULTRAVIOLET (UV) CURING SYSTEMS FIRST CHEMICAL CORPORATION (US) 1997-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224305-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARATION PROCESSES AND USES THEREOF AADAC, WIZ, CEBPZ CARM1 666/4885PRMT6 1521/4885MAPT 1887/4885
US-20130289124-A1 PHENYLCYCLOBUTYLAMIDE DERIVATIVES AND THEIR STEREOISOMERS, THE PREPARATION PROCESSES AND USES THEREOF AADAC, WIZ, CEBPZ CARM1 666/4885PRMT6 1521/4885MAPT 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.