Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597661 | 0.74 | CGAS (0.52) | MAPTKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL30839895 | 0.74 | CGAS (0.52) | MAPTKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL11098143 | 0.69 | GAA (0.41) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL675930 | 0.66 | KDM4E (0.46) | MAPTKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL10686771 | 0.65 | MAPT (0.52) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL14970288 | 0.65 | KDM4E (0.73) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL16209362 | 0.65 | KDM4E (0.73) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL22703276 | 0.65 | KDM4E (0.65) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL11236067 | 0.65 | KDM4E (0.54) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL7825295 | 0.65 | KDM4E (0.65) | MAPTKMT2AALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |