Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825295 | 1.00 | KDM4E (0.65) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27784542 | 0.85 | KDM4E (0.57) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27911749 | 0.83 | KDM4E (0.49) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7830543 | 0.79 | KDM4E (1.00) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14970288 | 0.77 | KDM4E (0.73) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209362 | 0.77 | KDM4E (0.73) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14970274 | 0.75 | KDM4E (0.56) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209378 | 0.75 | KDM4E (0.56) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209979 | 0.74 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16209975 | 0.74 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |