Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684672 | 0.89 | NOTUM (0.55) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL10691665 | 0.83 | NOTUM (0.66) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL25406664 | 0.77 | CYP17A1 (0.45) | NOTUMKEAP1CYP17A1 | |
| SCHEMBL10980403 | 0.73 | NOTUM (0.70) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21776985 | 0.72 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL10983173 | 0.70 | NOTUM (0.68) | NOTUMKEAP1 | |
| SCHEMBL10691838 | 0.70 | NOTUM (0.49) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21777007 | 0.69 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL4703323 | 0.68 | ADORA2A (0.39) | CYP17A1 | |
| SCHEMBL27150509 | 0.67 | CYP17A1 (0.36) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775762-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-04 | — | — | US | disclosed |