Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690034 | 0.83 | NOTUM (0.56) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL10983173 | 0.81 | NOTUM (0.68) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL14851143 | 0.75 | NOTUM (0.57) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL11102521 | 0.72 | NOTUM (1.00) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL14955603 | 0.72 | NOTUM (0.57) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL22163916 | 0.72 | KEAP1 (0.67) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL14964134 | 0.72 | NOTUM (0.64) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL10447781 | 0.72 | NOTUM (0.78) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL10984591 | 0.72 | NOTUM (1.00) | NOTUMKEAP1 | |
| SCHEMBL29875720 | 0.72 | CYP1A2 (0.45) | NOTUMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775762-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4775762-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-04 | — | — | US | disclosed |