Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350703 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL763105 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL31020835 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL12682909 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL1076966 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL16043542 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL31020834 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTMEN1KMT2A | |
| Bromide SCHEMBL18581998 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL17888445 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL16565613 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |