SCHEMBL10690041

SCHEMBL10690041

O=C1c2cccc3cccc(c23)C(=O)N1CCCn1ccnc1

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HEXA P06865 3/20 0.57
HEXB P07686 3/20 0.57
ESR1 P03372 1/20 0.55
ALOX15 P16050 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MAPK1 P28482 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
NR1I2 O75469 1/20 0.53
POLB P06746 1/20 0.53
AHR P35869 1/20 0.53
RAD52 P43351 1/20 0.53
RCE1 Q9Y256 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10688300 0.97 HEXA (0.59) HEXAHEXBESR1ALOX15HSD17B10
SCHEMBL10690695 0.96 HEXA (0.58) HEXAHEXBHSD17B10MEN1KMT2A
SCHEMBL10685366 0.96 HEXA (0.58) HEXAHEXBHSD17B10MEN1KMT2A
SCHEMBL10856878 0.87 ESR1 (0.64) ESR1ALOX15HSD17B10MAPK1NPSR1
SCHEMBL12780557 0.87 KMT2A (0.52) ESR1ALOX15HSD17B10MAPK1NPSR1
SCHEMBL10687742 0.87 KDM4E (0.48) HEXAHEXBESR1ALOX15HSD17B10
SCHEMBL13207604 0.85 CYP1B1 (0.51) HEXAHEXBALOX15HSD17B10NPSR1
SCHEMBL10688641 0.84 FTO (0.60) MEN1KMT2APOLBRAD52
SCHEMBL7424579 0.84 ESR1 (0.61) ESR1ALOX15HSD17B10MAPK1NPSR1
SCHEMBL23772131 0.83 ESR1 (0.60) ESR1ALOX15HSD17B10MAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105953-B Fluorescent molecule capable of being used for detecting methanol content in water and preparation method and application thereof 常州大学 2022-08-26 CN claimed
CN-113999204-A Achiral imidazole type ionic compound and preparation method and application thereof 常州大学 2022-02-01 CN claimed
US-4782064-A THROMBOXANE SYNTHETASE INHIBITORS AMERICAN CYANAMID CO. (US) 1988-11-01 US claimed
CN-114671853-B Green fluorescent molecule, preparation method and fluorescent color regulating and controlling method 常州大学 2023-09-26 CN disclosed
CN-113999204-B Achiral imidazole type ionic compound and preparation method and application thereof 常州大学 2023-09-05 CN disclosed
CN-114671853-A Green fluorescent molecule, preparation method and fluorescent color regulation method 常州大学 2022-06-28 CN disclosed
CN-113999204-A Achiral imidazole type ionic compound and preparation method and application thereof 常州大学 2022-02-01 CN disclosed