Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124920 | 0.82 | — | — | |
| SCHEMBL900572 | 0.78 | — | — | |
| SCHEMBL900731 | 0.78 | ALOX15 (0.35) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1069262 | 0.77 | MAPT (0.36) | ALDH1A1MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL407803 | 0.76 | MEN1 (0.31) | MEN1LMNAKMT2A | |
| SCHEMBL27683790 | 0.76 | — | — | |
| SCHEMBL1067407 | 0.76 | — | — | |
| SCHEMBL1068522 | 0.76 | — | — | |
| SCHEMBL27710279 | 0.74 | — | — | |
| SCHEMBL220664 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414233-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | Janssen Pharmaceutica NV (BE) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139428-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-17 | — | — | WO | disclosed |
| EP-3167716-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2017-05-17 | — | — | EP | disclosed |
| WO-2011006886-A2 | AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV | BASF SE (DE) | 2011-01-20 | — | — | WO | disclosed |
| WO-2010149758-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-29 | — | — | WO | disclosed |
| CN-101098870-B | Novel fused imidazole derivative | BANYU PHARMA CO LTD | 2010-11-03 | — | — | CN | disclosed |
| CN-101098870-A | Novel fused imidazole derivative | BANYU PHARMA CO LTD (JP) | 2008-01-02 | — | — | CN | disclosed |