Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.68 |
| ▸ | FBP1 | P09467 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690145 | 1.00 | GLO1 (0.68) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7272467 | 1.00 | GLO1 (0.68) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7279772 | 0.89 | GLO1 (0.64) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7483326 | 0.89 | GLO1 (0.64) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL6177870 | 0.88 | GLO1 (0.74) | GLO1FBP1KMT2ALMNANFE2L2 | |
| SCHEMBL9401844 | 0.86 | GLO1 (0.86) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7271725 | 0.86 | GLO1 (0.86) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7271722 | 0.86 | GLO1 (0.86) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL7277503 | 0.86 | GLO1 (0.86) | GLO1FBP1ALDH1A1KMT2ALMNA | |
| SCHEMBL1613935 | 0.84 | GLO1 (0.61) | GLO1FBP1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254064-A1 | 2-(Aminoalkylthio)methyl-1,4-dihydropyridine, a method for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-01-27 | — | — | EP | disclosed |