Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690311 | 0.89 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| SCHEMBL10685737 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| Hydrochloric Acid SCHEMBL10691971 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| SCHEMBL10690389 | 0.84 | SMN1; SMN2 (0.70) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| SCHEMBL10692077 | 0.80 | CYP1A2 (0.42) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| SCHEMBL10687438 | 0.78 | MAPK1 (0.39) | MAPTSMN1; SMN2RAB9AHCRTR1TP53 | |
| SCHEMBL10689387 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 | |
| SCHEMBL10690457 | 0.77 | NR4A2 (0.42) | MAPTSMN1; SMN2RAB9AHCRTR1TP53 | |
| SCHEMBL10693410 | 0.77 | HCRTR1 (0.39) | MAPTSMN1; SMN2RAB9AHCRTR1TP53 | |
| SCHEMBL10692304 | 0.77 | KMT2A (0.43) | ALDH1A1MAPTSMN1; SMN2RAB9AHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |