Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | ATP4A | P20648 | 4/20 | 0.42 |
| ▸ | ATP4B | P51164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692077 | 0.84 | CYP1A2 (0.42) | NR4A2ATP4AATP4BCYP1A2CYP2A6 | |
| SCHEMBL10689772 | 0.81 | NR4A2 (0.38) | NR4A2CYP1A2CYP2A6HSP90AB1KLKB1 | |
| SCHEMBL8182302 | 0.80 | GAA (0.45) | NR4A2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10685737 | 0.79 | SMN1; SMN2 (0.46) | CYP1A2KLKB1MAP4K1HCRTR1TP53 | |
| SCHEMBL31669621 | 0.79 | ATP4A (0.54) | NR4A2ATP4AATP4BRAB9A | |
| SCHEMBL10692146 | 0.78 | NOTUM (0.36) | NR4A2CYP1A2CYP2A6KLKB1MAP4K1 | |
| SCHEMBL10692304 | 0.78 | KMT2A (0.43) | NR4A2CYP1A2CYP2A6KLKB1MAP4K1 | |
| SCHEMBL10693751 | 0.78 | ATP4A (0.44) | ATP4AATP4BCYP1A2CYP2A6KLKB1 | |
| SCHEMBL10690142 | 0.77 | ALDH1A1 (0.49) | CYP1A2CYP2A6KLKB1MAP4K1HCRTR1 | |
| SCHEMBL10690311 | 0.77 | SMN1; SMN2 (0.47) | CYP1A2HCRTR1TP53MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |