Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | APEX1 | P27695 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695242 | 0.94 | NR1I2 (0.60) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10695061 | 0.94 | TDP1 (0.66) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10696537 | 0.92 | NR1I2 (0.72) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10695981 | 0.91 | NR1I2 (0.61) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9602363 | 0.91 | NR1I2 (0.59) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9500054 | 0.90 | TDP1 (0.61) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10693004 | 0.88 | TDP1 (0.63) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10694770 | 0.88 | TDP1 (0.58) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10697178 | 0.87 | NR1I2 (0.60) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL10696696 | 0.86 | NR1I2 (0.61) | NR1I2PGRESR1PPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0153709-A2 | Novel cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |