Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921645 | 0.83 | PIM1 (0.76) | PIM1KDM1AMAOALMNAKMT2A | |
| Iodide SCHEMBL31634400 | 0.81 | PIM1 (0.73) | PIM1KDM1AMAOALMNAKMT2A | |
| Iodide SCHEMBL31634399 | 0.81 | PIM1 (0.73) | PIM1KDM1AMAOALMNAKMT2A | |
| Hydrochloric Acid SCHEMBL14697550 | 0.81 | PIM1 (0.73) | PIM1KDM1AMAOALMNAKMT2A | |
| SCHEMBL1649654 | 0.79 | PIM1 (0.89) | PIM1KDM1ALMNAKMT2AMEN1 | |
| SCHEMBL29557425 | 0.77 | KDM1A (0.61) | PIM1KDM1APTGS1PTGS2MAOA | |
| SCHEMBL293951 | 0.77 | KDM1A (0.61) | PIM1KDM1APTGS1PTGS2MAOA | |
| SCHEMBL9077379 | 0.77 | PTGS1 (0.58) | PIM1KDM1APTGS1PTGS2MAOA | |
| SCHEMBL1581710 | 0.77 | KDM1A (0.53) | PIM1KDM1APTGS1PTGS2MAOA | |
| SCHEMBL208025 | 0.76 | PIM1 (0.79) | PIM1KDM1ALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265520-A1 | MODIFIED ASPHALT COMPOSITIONS | The Lubrizol Corporation (US) | 1988-05-04 | — | — | EP | disclosed |
| WO-1987006947-A1 | MODIFIED ASPHALT COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1987-11-19 | — | — | WO | disclosed |
| US-4677146-A | Modified asphalt compositions comprising a nitrogen derivative of an esterified copolymer | THE LUBRIZOL CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-3933761-A | INTERPOLYMERS | THE LUBRIZOL CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |