SCHEMBL2921645

SCHEMBL2921645

NCCN1c2ccccc2Sc2ccccc21

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.76
KDM1A O60341 9/20 0.59
LMNA P02545 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
SIGMAR1 Q99720 2/20 0.56
SLC22A1 O15245 1/20 0.56
PRNP P04156 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
ADRB2 P07550 1/20 0.56
CHRM2 P08172 1/20 0.56
CHRM4 P08173 1/20 0.56
HTR1A P08908 1/20 0.56
CHRM5 P08912 1/20 0.56
ADRA2A P08913 1/20 0.56
CYP2D6 P10635 1/20 0.56
CHRM1 P11229 1/20 0.56
DRD2 P14416 1/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL31634400 0.98 PIM1 (0.73) PIM1KDM1ALMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL14697550 0.98 PIM1 (0.73) PIM1KDM1ALMNAMEN1KMT2A
Iodide SCHEMBL31634399 0.98 PIM1 (0.73) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL1649654 0.88 PIM1 (0.89) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL14707051 0.85 ITGB2 (0.68) PIM1KDM1ALMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL14697324 0.84 ITGB2 (0.67) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL10690359 0.83 PIM1 (0.63) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL208025 0.81 PIM1 (0.79) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL2595053 0.79 LMNA (0.62) PIM1KDM1ALMNAMEN1KMT2A
SCHEMBL627548 0.79 KDM1A (0.59) PIM1KDM1ALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120201857-A Method for preparing solar cell by in-situ passivation of perovskite film by using diphenylamino ammonium salt and derivative 大连理工大学 2025-06-24 CN disclosed
WO-2025120367-A1 FUSED-RING POLYCYCLIC AMINE FUNCTIONALIZED OLEFINIC POLYMERS FOR LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-12 WO disclosed
US-20250188379-A1 FUSED-RING POLYCYCLIC AMINE FUNCTIONALIZED OLEFINIC POLYMERS FOR LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-12 US disclosed
EP-4153350-A1 MODIFIED CLAY SORBENTS WITH MULTIFUNCTIONAL QUATERNARY AMMONIUM COMPOUNDS AND MONO-QUATERANRY AMMONIUM COMPOUNDS AND METHODS OF SORBING PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) FROM CONTAMINATED SAMPLES WITH THE MODIFIED CLAY SORBENTS Specialty Minerals (Michigan) Inc. (US) 2023-03-29 EP disclosed
US-9540358-B2 Tricyclic compounds as anticancer agents ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2017-01-10 US disclosed
US-20140213578-A1 TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS MT. SINAI SCHOOL OF MEDICINE (US) 2014-07-31 US disclosed
EP-0848053-B1 Mixtures of esterified carboxy-containing interpolymers and lubricants containing them LUBRIZOL CORP (US) 2010-09-29 EP disclosed
EP-1200541-B1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM LUBRIZOL CORP (US) 2010-02-10 EP disclosed
EP-0743353-B2 Additive combinations for lubricants and functional fluids LUBRIZOL CORP (US) 2008-08-06 EP disclosed
EP-1326611-B1 AZA- AND POLYAZA-NAPHTHALENYL-CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS MERCK & CO INC (US) 2007-06-13 EP disclosed
WO-1986003221-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1986-06-05 WO disclosed
EP-0002286-B1 LUBRICANT OR FUEL ROHM AND HAAS COMPANY (US) 1984-07-04 EP disclosed
US-4411804-A CONTAINING GRAPHITE, MOLYBDENUM DISULFIDE, OR ZINC OXIDE AND FLOW CONTROL AGENT ATLANTIC RICHFIELD COMPANY (US) 1983-10-25 US disclosed
US-4292185-A COMPRISING A DIENE-MODIFIED MONOOLEFINIC POLYMER REACTED WITH CHLOROSULFONYL ISOCYANATE AND THEN WITH AN AMINE ROHM AND HAAS COMPANY (US) 1981-09-29 US disclosed
US-4160739-A Polyolefinic copolymer additives for lubricants and fuels ROHM AND HAAS COMPANY (US) 1979-07-10 US disclosed
EP-0002286-A2 Lubricant or fuel ROHM AND HAAS COMPANY (US) 1979-06-13 EP disclosed
US-4136040-A ALSO INCLUDING A NITROGEN CONTAINING MIXED ESTER OF AN OLEFIN ALPHA, B-UNSATURATED ACID OR ANHYDRIDE COPOLYMER ATLANTIC RICHFIELD COMPANY (US) 1979-01-23 US disclosed
US-4029783-A CARDIOTONIC, VASODILATION BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-06-14 US disclosed
US-3998810-A CARDIAC AND CIRCULATORY ACTIVITY BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-12-21 US disclosed
US-3933761-A INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213578-A1 TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS TFEB, FOXO3, FOXO1 PIM1 2156/4885KDM1A 2457/4885LMNA 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.