Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690315 | 0.88 | TSHR (0.48) | CHRM2CHRM3CHRM5TSHRHPGD | |
| SCHEMBL10690318 | 0.88 | TSHR (0.48) | CHRM2CHRM3CHRM5TSHRHPGD | |
| SCHEMBL10685270 | 0.88 | TSHR (0.48) | CHRM2CHRM3CHRM5TSHRMOGAT2 | |
| SCHEMBL10685265 | 0.88 | TSHR (0.48) | CHRM2CHRM3CHRM5TSHRMOGAT2 | |
| SCHEMBL10686949 | 0.87 | CHRM2 (0.38) | CHRM2CHRM3CHRM5TSHRMOGAT2 | |
| SCHEMBL1582778 | 0.86 | TSHR (0.50) | CHRM2CHRM3CHRM5TSHRTDP1 | |
| SCHEMBL1582360 | 0.86 | TSHR (0.50) | CHRM2CHRM3CHRM5TSHRHPGD | |
| SCHEMBL1582831 | 0.86 | TSHR (0.50) | CHRM2CHRM3CHRM5TSHRTDP1 | |
| SCHEMBL1582359 | 0.86 | TSHR (0.50) | CHRM2CHRM3CHRM5TSHRHPGD | |
| SCHEMBL10689132 | 0.84 | UCHL3 (0.43) | CHRM2CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755323-A | Mixture of liquid crystalline compounds including substituted para-dioxane | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |