UCHL3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3669327	0.60	2/20
SCHEMBL195220	0.59	2/20
SCHEMBL258104	0.53	2/20
SCHEMBL919089	0.53	2/20
SCHEMBL5275137	0.48	2/20
SCHEMBL6316296	0.44	2/20
SCHEMBL6316299	0.44	2/20
SCHEMBL597719	0.44	2/20
SCHEMBL6278957	0.38	2/20
SCHEMBL955786	0.37	2/20
Menadione (SCHEMBL25970)	1.00	1/20
Perifosine (SCHEMBL93872)	1.00	1/20
Menadione (SCHEMBL1364028)	1.00	1/20
SCHEMBL5700581	1.00	1/20
SCHEMBL5700584	1.00	1/20
SCHEMBL5819833	1.00	1/20
Menadione (SCHEMBL987664)	0.95	1/20
Menadione (SCHEMBL3411128)	0.95	1/20
Menadione (SCHEMBL6680739)	0.95	1/20
Menadione (SCHEMBL4778555)	0.88	1/20

Clinical trials — most relevant to UCHL3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Relapsed and/or Refractory Non-Hodgkin Lymphoma Study	PHASE2	WITHDRAWN
Olaparib in Patients With HRD Malignant Mesothelioma	PHASE2	RECRUITING
Studying TAK-243 in Patients With Advanced Cancer	PHASE1	RECRUITING
Cerebrolysin in Prevention of Postoperative Delirium in Cardiac Surgery	nan	UNKNOWN
Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer's Disease	nan	COMPLETED
Evaluation of Biomarker Kinetics After Mild Brain Injury Trauma	nan	COMPLETED
Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) to Exclude Lesions Linked to Significant Traumatic Brain Injuries	nan	RECRUITING
Neuronal and Glial Biomarkers in Stroke	nan	COMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion	nan	COMPLETED
Single-center Transversal Observational Study on the Evaluation of S100B Changes in Subjects Attending the Emergency Department With Head Trauma	nan	RECRUITING
Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma	nan	NOT_YET_RECRUITING
VIDAS® TBI Real Life Performance in Subjects With Mild Traumatic Brain Injury (mTBI)	nan	COMPLETED
Validating a Blood Test for the Detection of Traumatic Brain Injury in Children	nan	RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Prediction of Delayed Cognitive Impairment in Cardiac Arrest Survivors With Good Neurological Outcomes	nan	ENROLLING_BY_INVITATION
Systemic Biomarkers of Brain Injury From Hyperammonemia	nan	RECRUITING
Neuronal Damage In Delirium Study	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
BRAINI-2 Elderly Mild TBI European Study	nan	COMPLETED
Transforming Research and Clinical Knowledge in TBI Pilot	nan	COMPLETED
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit	nan	COMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
Biological Markers in Parkinson's Disease	nan	COMPLETED
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome	nan	RECRUITING
Assessment of the Effects of Concussion on Adolescent Rugby Union Players	nan	COMPLETED
Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a UCHL3 binder may also engage these)

Protein	Name	Similarity
Q2TBG8	—	1.000	Q2TBG8 →
Q9JKB1	—	1.000	Q9JKB1 →
Q06AB3	—	1.000	Q06AB3 →
Q91Y78	—	1.000	Q91Y78 →
P50103	—	0.994	P50103 →
Q8GWE1	—	0.979	Q8GWE1 →
P58321	—	0.969	P58321 →
P23356	—	0.968	P23356 →
Q60HC8	—	0.966	Q60HC8 →
UCHL1	Ubiquitin carboxyl-terminal hydrolase isozyme L1	0.963	landscape →
Q9GM50	—	0.962	Q9GM50 →
Q9R0P9	—	0.951	Q9R0P9 →
Q9FFF2	—	0.939	Q9FFF2 →
Q567B1	—	0.939	Q567B1 →
O04482	—	0.938	O04482 →
Q5R8R4	—	0.936	Q5R8R4 →
Q5RGJ5	—	0.934	Q5RGJ5 →
A0FKG7	—	0.933	A0FKG7 →
Q6DI37	—	0.932	Q6DI37 →
Q13867	—	0.931	Q13867 →
P70645	—	0.931	P70645 →
Q8R016	—	0.930	Q8R016 →
Q9Y6W3	—	0.930	Q9Y6W3 →
Q5ZJJ8	—	0.930	Q5ZJJ8 →
Q9R1S8	—	0.929	Q9R1S8 →
Q2KJD7	—	0.929	Q2KJD7 →
Q64514	—	0.928	Q64514 →
Q5R407	—	0.928	Q5R407 →
Q6IQS6	—	0.928	Q6IQS6 →
B4G0F3	—	0.928	B4G0F3 →