Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869424 | 0.82 | KDM4E (0.50) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL3072249 | 0.80 | KDM4E (0.48) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL867509 | 0.77 | KDM4E (0.46) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL155737 | 0.77 | KDM4E (0.46) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL13146690 | 0.77 | KDM4E (0.55) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL299064 | 0.77 | KDM4E (0.46) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL13174904 | 0.74 | HDAC4 (0.48) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL19721706 | 0.74 | KDM4E (0.46) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL13191774 | 0.73 | — | — | |
| SCHEMBL5759550 | 0.73 | DPP4 (0.53) | KDM4ERAB9AL3MBTL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788207-A | Photoactivated miticidal and insecticidal ethynylthiazoles | FMC CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |