SCHEMBL3072249

SCHEMBL3072249

c1csc(-c2cnc(-c3cccs3)s2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.48
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 3/20 0.48
EPHX2 P34913 1/20 0.48
RAB9A P51151 5/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
NPC1 O15118 3/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
GAA P10253 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44
CYP2E1 P05181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869424 0.98 KDM4E (0.50) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL19721706 0.94 KDM4E (0.46) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL2246884 0.90 DPP4 (0.47) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL10630430 0.86 ALDH1A1 (0.42) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL10630396 0.86 KDM4E (0.41) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL13174904 0.85 HDAC4 (0.48) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL10716636 0.81 ALDH1A1 (0.52) KDM4EALDH1A1HSD17B10EPHX2RAB9A
SCHEMBL10625604 0.81 ABL1 (0.45) KDM4EALDH1A1RAB9AL3MBTL1NPC1
SCHEMBL10626225 0.81 RAB9A (0.52) KDM4EALDH1A1RAB9AL3MBTL1NPC1
SCHEMBL10628236 0.81 ALDH1A1 (0.49) KDM4EALDH1A1HSD17B10RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103467464-B Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2015-04-15 CN claimed
CN-103467464-A Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2013-12-25 CN claimed
CN-103848969-B One contains thiazole and thiazole-dibenzothiophene benzo two thiophen polymer and preparation and application thereof Haiyangwang Lighting Technology Co., Ltd. (CN) 2016-03-30 CN disclosed
CN-103467464-B Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2015-04-15 CN disclosed
CN-103467464-B Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2015-04-15 CN disclosed
CN-103467464-B Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2015-04-15 CN disclosed
CN-103467464-A Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2013-12-25 CN disclosed
CN-103467464-A Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2013-12-25 CN disclosed
CN-103467464-A Mosquito killing activity of 2,5-dithienylthiazole derivatives UNIV NANKAI 2013-12-25 CN disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-4892678-A DOPED WITH AN ANION; SEMICONDUCTOR AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1990-01-09 US disclosed
US-4877852-A SEMICONDUCTOR MATERIALS AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-10-31 US disclosed