Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21991863 | 0.82 | PPARG (0.51) | PPARGPPARASLC6A9FFAR1SLC6A4 | |
| SCHEMBL21991923 | 0.78 | FNTA (0.51) | PPARGPPARASLC6A9FFAR1MEN1 | |
| SCHEMBL21991857 | 0.77 | NPC1 (0.44) | PPARGPPARASLC6A9FFAR1NPC1 | |
| SCHEMBL21992648 | 0.76 | PPARG (0.46) | PPARGPPARASLC6A9SLC6A4SLC6A2 | |
| SCHEMBL21991266 | 0.75 | PPARG (0.43) | PPARGPPARASLC6A9FFAR1 | |
| SCHEMBL21991294 | 0.75 | PPARG (0.45) | PPARGPPARASLC6A9CYP3A4 | |
| SCHEMBL987532 | 0.74 | PPARG (0.44) | PPARGPPARASLC6A9FFAR1ALOX5 | |
| SCHEMBL987529 | 0.74 | PPARG (0.44) | PPARGPPARASLC6A9FFAR1ALOX5 | |
| SCHEMBL21991320 | 0.74 | NPC1 (0.41) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL15473214 | 0.73 | SLC6A4 (0.44) | PPARGPPARASLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4744812-A | HALOGENATED DIPHENYL ETHER | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |
| US-4632696-A | POSTEMERGENCE, PREEMERGENCE APPLICATIONS | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-30 | — | — | US | disclosed |
| US-4497651-A | Dichloroquinoline derivatives for use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1985-02-05 | — | — | US | disclosed |
| US-4494983-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-22 | — | — | US | disclosed |
| US-4422864-A | Cyclohexanedione derivatives, their preparation and herbicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| US-4363651-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | disclosed |