SCHEMBL987532

SCHEMBL987532

CCC(=CC(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.44
ALOX5 P09917 4/20 0.44
PSEN1 P49768 4/20 0.44
PPARA Q07869 2/20 0.42
SLC6A9 P48067 6/20 0.41
FFAR1 O14842 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPK14 Q16539 1/20 0.40
PTGES O14684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987529 1.00 PPARG (0.44) PPARGALOX5PSEN1PPARASLC6A9
SCHEMBL8825481 0.82 PDE4A (0.39) PPARGPPARAMEN1KMT2A
SCHEMBL4939976 0.76 MEN1 (0.43) PPARGPPARASLC6A9MEN1KMT2A
SCHEMBL134523 0.76 MEN1 (0.43) PPARGPPARASLC6A9MEN1KMT2A
SCHEMBL10998771 0.75 SCN9A (0.42) PPARGPPARAMEN1KMT2A
SCHEMBL10675620 0.75 SCN9A (0.42) PPARGPPARAMEN1KMT2A
SCHEMBL10690637 0.74 PPARG (0.44) PPARGALOX5PSEN1PPARASLC6A9
SCHEMBL732546 0.74 ALDH1A1 (0.42) PPARGPPARAMEN1KMT2A
SCHEMBL732547 0.74 ALDH1A1 (0.42) PPARGPPARAMEN1KMT2A
SCHEMBL136831 0.74 CYP1A2 (0.54) PPARGPPARASLC6A9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160349088-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES PATEL GORDHANBHAI (US) 2016-12-01 US disclosed
EP-2475612-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES JP LABORATORIES, INC. (US) 2012-07-18 EP disclosed
WO-2011031959-A1 MONITORING DEVICES AND PROCESSES BASED ON TRANSFORMATION, DESTRUCTION AND CONVERSION OF NANOSTRUCTURES JP LABORATORIES, INC. (US) 2011-03-17 WO disclosed
US-20110003279-A1 Monitoring devices and processes based on transformation, destruction and conversion of nanostructures PATEL GORDHANBHAI NATHALAL 2011-01-06 US disclosed
EP-0882498-B1 Process for producing a solvent-less O/W type emulsion HODOGAYA CHEMICAL CO LTD (JP) 2004-02-11 EP disclosed
EP-0788740-B1 Composite particle aqueous suspension and process for producing same HODOGAYA CHEMICAL CO LTD (JP) 2003-04-16 EP disclosed
US-6153657-A EXCELLENT STABILITY FOR STORAGE AND WATER-DILUTION HODOGAYA CHEMICAL CO., LTD. (JP) 2000-11-28 US disclosed
EP-0882498-A2 Process for producing a solvent-less O/W type emulsion HODOGAYA CHEMICAL CO LTD (JP) 1998-12-09 EP disclosed
EP-0788740-A1 Composite particle aqueous suspension and process for producing same HODOGAYA CHEMICAL CO LTD (JP) 1997-08-13 EP disclosed