Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 6/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.60 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.60 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836763 | 1.00 | KDM5A (0.60) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL9835961 | 1.00 | KDM5A (0.60) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL9835679 | 1.00 | KDM5A (0.60) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL9836344 | 0.98 | KDM5A (0.59) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL27995857 | 0.87 | KDM5A (0.56) | KDM5AKDM4CPHF8KDM5CKDM5B | |
| SCHEMBL14435161 | 0.82 | GPR84 (0.58) | KDM5AKDM4CPHF8GPR84PPARG | |
| SCHEMBL2052582 | 0.82 | GPR84 (0.58) | KDM5AKDM4CPHF8GPR84PPARG | |
| SCHEMBL1115961 | 0.82 | GPR84 (0.58) | KDM5AKDM4CPHF8GPR84PPARG | |
| SCHEMBL29101396 | 0.82 | GPR84 (0.58) | KDM5AKDM4CPHF8GPR84PPARG | |
| SCHEMBL17272316 | 0.82 | GPR84 (0.58) | KDM5AKDM4CPHF8GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734425-A | CARDIOVASCULAR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |