Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 11/20 | 0.40 |
| ▸ | TGFBR2 | P37173 | 5/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691008 | 0.78 | AOC3 (0.35) | TGFBR1AOC3 | |
| SCHEMBL4486939 | 0.73 | CCR1 (0.46) | CCR1CCR8TGFBR1TGFBR2CYP2A6 | |
| Hydrochloric Acid SCHEMBL4465754 | 0.71 | CCR1 (0.43) | CCR1CCR8TGFBR1TGFBR2CYP2A6 | |
| SCHEMBL4167622 | 0.68 | CCR1 (0.71) | CCR1CCR8TGFBR1TGFBR2CYP2A6 | |
| SCHEMBL30509464 | 0.68 | CCR1 (0.64) | CCR1CCR8TGFBR1TGFBR2HTR3E | |
| SCHEMBL15984940 | 0.68 | CCR1 (0.64) | CCR1CCR8TGFBR1TGFBR2HTR3E | |
| SCHEMBL4473970 | 0.68 | CCR1 (0.40) | CCR1CCR8TGFBR1TGFBR2ADORA2A | |
| SCHEMBL196966 | 0.67 | CCR1 (1.00) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL30511194 | 0.67 | CCR1 (1.00) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL29388304 | 0.67 | CCR1 (1.00) | CCR1CCR8TGFBR1CYP2A6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |