Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690799 | 0.78 | CCR1 (0.47) | AOC3TGFBR1 | |
| SCHEMBL10690694 | 0.78 | KCNH2 (0.35) | KCNH2CTSSCTSKTGFBR1PDE10A | |
| SCHEMBL10688549 | 0.74 | KCNH2 (0.34) | KCNH2CTSSCTSKTGFBR1PDE10A | |
| SCHEMBL9822676 | 0.70 | KCNH2 (0.43) | KCNH2TGFBR1PDE10A | |
| SCHEMBL9822971 | 0.69 | KCNH2 (0.49) | KCNH2TGFBR1PDE10A | |
| SCHEMBL10698102 | 0.68 | KCNH2 (0.42) | KCNH2CTSSCTSKTGFBR1PDE10A | |
| SCHEMBL10371265 | 0.68 | NOS1 (0.44) | KCNH2CTSSCTSKTGFBR1 | |
| SCHEMBL2522650 | 0.67 | KCNH2 (0.67) | KCNH2CTSSCTSK | |
| SCHEMBL16622421 | 0.67 | KCNH2 (0.47) | KCNH2CTSSCTSK | |
| SCHEMBL9822815 | 0.67 | HTT (0.35) | AOC3KCNH2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |