Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623484 | 0.90 | CYP3A4 (0.58) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL22173826 | 0.90 | CYP3A4 (0.67) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL15581115 | 0.88 | TERT (0.61) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL15131700 | 0.87 | CYP3A4 (0.61) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL28755396 | 0.84 | TERT (0.64) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL15131712 | 0.84 | TERT (0.64) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL121858 | 0.82 | CYP3A4 (0.73) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL29388988 | 0.82 | CYP3A4 (0.73) | CYP3A4TSHRMAPK1TERTCD44 | |
| SCHEMBL6012957 | 0.82 | TSHR (0.41) | CYP3A4TSHRMAPK1TERTALDH1A1 | |
| SCHEMBL29429002 | 0.82 | PTK2 (0.64) | CYP3A4TSHRMAPK1TERTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792508-A | STEREOISOMERIC NAPHTHALENE IMIDAZOLE PERYLENES, ARYL AMINES | XEROX CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0042753-B1 | NONAPEPTIDE AND DECAPEPTIDE AGONISTS OF LUTEINIZING HORMONE RELEASING HORMONE CONTAINING HETEROCYCLIC AMINO ACID RESIDUES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM, AND THEIR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |