Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219667 | 0.86 | ALDH1A1 (0.54) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL7217728 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL12243012 | 0.84 | SMN1; SMN2 (0.68) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL4210730 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL7223234 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL14179083 | 0.83 | CA1 (0.59) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL17549763 | 0.83 | MAPK1 (0.63) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL2963432 | 0.81 | CYP2C19 (0.56) | ALDH1A1POLBGAAKDM4ETDP1 | |
| SCHEMBL14803849 | 0.81 | TSHR (0.64) | ALDH1A1GAAKDM4ETDP1ALOX12 | |
| SCHEMBL8404954 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBGAAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |