Biphenyl

Biphenyl

SCHEMBL1069092

CCCC[Sn]CCCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.42
HPGD P15428 2/20 0.40
GAA P10253 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
HSD11B1 P28845 2/20 0.38
GPR84 Q9NQS5 1/20 0.38
POLB P06746 1/20 0.38
PCSK9 Q8NBP7 1/20 0.38
MAPT P10636 1/20 0.38
LTA4H P09960 1/20 0.38
NR1H3 Q13133 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL10855994 0.84 TSHR (0.50) TSHRHPGDSMN1; SMN2HSD11B1PCSK9
Biphenyl SCHEMBL5868585 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHPGDGAAHDAC3
Biphenyl SCHEMBL15347228 0.82 ALDH1A1 (0.56) ALDH1A1TSHRHPGDGAAHDAC3
Biphenyl SCHEMBL27853080 0.79 ALDH1A1 (0.53) ALDH1A1TSHRSMN1; SMN2MMP2MMP9
Hexadecane SCHEMBL8524813 0.79 ALDH1A1 (0.53) ALDH1A1TSHRSMN1; SMN2MMP2MMP9
Biphenyl SCHEMBL27342649 0.79 ALDH1A1 (0.53) ALDH1A1TSHRSMN1; SMN2MMP2MMP9
Biphenyl SCHEMBL16196748 0.79 ALDH1A1 (0.53) ALDH1A1TSHRHPGDGAAHDAC3
Biphenyl SCHEMBL5868587 0.79 ALDH1A1 (0.53) ALDH1A1TSHRSMN1; SMN2MMP2MMP9
Dodecane SCHEMBL27916009 0.79 ALDH1A1 (0.53) ALDH1A1TSHRSMN1; SMN2MMP2MMP9
Benzyl Alcohol SCHEMBL29086137 0.79 TSHR (0.56) TSHRSMN1; SMN2PCSK9LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316897-A Silicone sealant and preparation method thereof 广东高士高科实业有限公司 2022-04-12 CN claimed
CN-117344554-A Basalt fiber anti-discoloration water-based paint, preparation method and basalt fiber product 中科瑞丽分离科技无锡有限公司 2024-01-05 CN disclosed
CN-115769364-A Metal oxide diffusion barrier 朗姆研究公司 2023-03-07 CN disclosed
CN-114316897-A Silicone sealant and preparation method thereof 广东高士高科实业有限公司 2022-04-12 CN disclosed
CN-111727272-A Method for producing metal-containing film 巴斯夫欧洲公司 2020-09-29 CN disclosed
CN-111727271-A Method for producing metal-containing film 巴斯夫欧洲公司 2020-09-29 CN disclosed
EP-2578626-B1 RUBBER COMPOSITION FOR TIRE INSULATIONS AND TIRE USING SAME SUMITOMO RUBBER IND (JP) 2016-03-30 EP disclosed
EP-2987826-A1 TIRE AND METHOD FOR PRODUCING TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-02-24 EP disclosed
US-20160046790-A1 TIRE AND METHOD FOR MANUFACTURING TIRE SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2016-02-18 US disclosed
US-8993666-B2 Rubber composition for insulation of tire and tire using same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-03-31 US disclosed
US-20120285601-A1 RUBBER COMPOSITION FOR SIDEWALL AND TIRE HAVING SIDEWALL USING THEREOF, AND RUBBER COMPOSITION FOR CLINCH AND TIRE HAVING CLINCH USING THEREOF MIYAZAKI TATSUYA (JP) 2012-11-15 US disclosed
US-8258213-B2 Rubber composition for breaker topping SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-09-04 US disclosed
US-20110094649-A1 RUBBER COMPOSITION FOR SIDEWALL AND TIRE HAVING SIDEWALL USING THEREOF, AND RUBBER COMPOSITION FOR CLINCH AND TIRE HAVING CLINCH USING THEREOF SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-28 US disclosed
EP-2159074-B1 Rubber composition for cap tread and tire having cap tread comprising the same SUMITOMO RUBBER IND (JP) 2011-01-19 EP disclosed
US-20100224299-A1 RUBBER COMPOSITION FOR TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-09-09 US disclosed
US-20100227955-A1 RUBBER COMPOSITION FOR BREAKER TOPPING SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-09-09 US disclosed
EP-2159074-A1 Rubber composition for cap tread and tire having cap tread comprising the same SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-03-03 EP disclosed
US-20100036019-A1 RUBBER COMPOSITION FOR CAP TREAD AND TIRE HAVING CAP TREAD COMPRISING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-02-11 US disclosed
US-4508916-A Curable substituted urethane acrylates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-02 US disclosed
US-4281076-A CURING AT LOW TEMPERATURE, COMPRISING A DIBASIC ACID, A BLOCKED ISOCYANATE AND A TIN COMPOUND KANSAI PAINT COMPANY, LIMITED (JP) 1981-07-28 US disclosed