Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.83 |
| ▸ | PGR | P06401 | 3/20 | 0.83 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.64 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640295 | 0.94 | NR1I2 (0.73) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9702948 | 0.93 | NR1I2 (0.86) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9702941 | 0.93 | NR1I2 (0.86) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10633665 | 0.93 | NR1I2 (0.80) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11109175 | 0.92 | NR1I2 (0.84) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11109161 | 0.92 | NR1I2 (0.84) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL9659869 | 0.91 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL152861 | 0.91 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL16072811 | 0.91 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL10492342 | 0.91 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727071-A | MICROBIOCIDES | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| US-4598154-A | Thiazole intermediates for cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |