Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688730 | 1.00 | CA12 (0.52) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL8972761 | 0.86 | L3MBTL1 (0.52) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL13668076 | 0.86 | CA1 (0.51) | CA1CA2L3MBTL1MAPK14ALDH1A1 | |
| SCHEMBL24142085 | 0.85 | L3MBTL1 (0.51) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL28404546 | 0.85 | L3MBTL1 (0.51) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL28404547 | 0.85 | L3MBTL1 (0.51) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL9483698 | 0.85 | L3MBTL1 (0.51) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL16898288 | 0.85 | L3MBTL1 (0.55) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL16898289 | 0.85 | L3MBTL1 (0.55) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL9482265 | 0.85 | L3MBTL1 (0.51) | CA12CA1CA2CA9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725687-A | ANTITUMOR AGENTS; SIDE EFFECT REDUCTION; POTENCY | SOUTHERN RESEARCH INSTITUTE (US) | 1988-02-16 | — | — | US | disclosed |