Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TOP2A | P11388 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748540 | 0.97 | KDM4E (0.71) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9184515 | 0.97 | KDM4E (0.71) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10561159 | 0.96 | KDM4E (0.70) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10557701 | 0.92 | KDM4E (0.65) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9750278 | 0.91 | KDM4E (0.69) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9703656 | 0.90 | KDM4E (0.70) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10839628 | 0.89 | KDM4E (0.68) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9748511 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10480355 | 0.87 | KDM4E (0.68) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10480278 | 0.87 | KDM4E (0.66) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775668-A | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids and anti-bacterial use thereof | PFIZER INC. (US) | 1988-10-04 | — | — | US | claimed |