SCHEMBL10691065

SCHEMBL10691065

NS(=O)(=O)c1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.80
CA12 O43570 14/20 0.80
CA1 P00915 14/20 0.80
CA9 Q16790 13/20 0.80
CA7 P43166 6/20 0.80
CA14 Q9ULX7 5/20 0.80
CA6 P23280 5/20 0.80
CA5A P35218 5/20 0.80
CA5B Q9Y2D0 5/20 0.80
CA13 Q8N1Q1 4/20 0.80
CA3 P07451 4/20 0.80
CA4 P22748 3/20 0.80
PLA2G7 Q13093 1/20 0.80
HTR6 P50406 2/20 0.70
SOS1 Q07889 1/20 0.59
USP2 O75604 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
AGO2 Q9UKV8 1/20 0.54
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19479299 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
SCHEMBL10493509 0.89 CA2 (0.68) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL29825137 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL6868390 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL1332409 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL28257999 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL729 0.89 CA2 (1.00) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL7517039 0.87 CA2 (0.94) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL3100364 0.87 CA2 (0.94) CA2CA12CA1CA9CA7
Benzenesulfonamide SCHEMBL1009443 0.87 CA2 (0.94) CA2CA12CA1CA9CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260833-A2 Process for producing polyamide acid having siloxane bonds and polyimide having siloxane bonds and isoindoloquinazolinedione rings HITACHI CHEMICAL COMPANY (JP) 1988-03-23 EP disclosed