Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18242250 | 0.86 | HTT (0.41) | RECQLHTTALDH1A1 | |
| SCHEMBL10062452 | 0.81 | RECQL (0.41) | RECQLHTTCNR2CYSLTR2CYSLTR1 | |
| SCHEMBL22358954 | 0.81 | CYSLTR2 (0.47) | RECQLHTTCYSLTR2CYSLTR1PPARG | |
| SCHEMBL23169058 | 0.81 | CYSLTR2 (0.47) | RECQLHTTCYSLTR2CYSLTR1PPARG | |
| SCHEMBL10060891 | 0.81 | PPARG (0.45) | RECQLHTTCNR2CYSLTR2CYSLTR1 | |
| SCHEMBL27604824 | 0.80 | SLC2A1 (0.41) | RECQLHTTCYSLTR2CYSLTR1CSNK1E | |
| SCHEMBL23190512 | 0.80 | RECQL (0.43) | RECQLHTTCYSLTR2CYSLTR1PPARG | |
| SCHEMBL8499483 | 0.80 | PPARG (0.47) | RECQLCYSLTR2CYSLTR1PPARGPRSS1 | |
| SCHEMBL9646398 | 0.80 | PPARG (0.47) | RECQLCYSLTR2CYSLTR1PPARGPRSS1 | |
| SCHEMBL6152931 | 0.80 | PPARG (0.47) | RECQLCYSLTR2CYSLTR1PPARGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727073-A | CEREBOVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0177287-A2 | Pyrimidine derivatives, processes for preparation thereof and composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |