Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23190512 | 0.98 | RECQL (0.43) | RECQLHTTTSHRCSNK1EALDH1A1 | |
| SCHEMBL23730871 | 0.86 | HTT (0.41) | RECQLHTTTSHRALDH1A1CYP2C19 | |
| SCHEMBL6678854 | 0.86 | TSHR (0.43) | TSHRCSNK1EALDH1A1OPRM1CNR2 | |
| SCHEMBL6684349 | 0.84 | CSNK1E (0.42) | TSHRCSNK1EALDH1A1OPRM1CNR2 | |
| SCHEMBL5795839 | 0.83 | HTT (0.39) | HTTTSHRALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL31627096 | 0.82 | SLC7A5 (0.38) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL31627099 | 0.82 | CYP2C19 (0.42) | HTTTSHRALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL10691434 | 0.81 | RECQL (0.41) | RECQLHTTCSNK1EALDH1A1CNR2 | |
| SCHEMBL23169058 | 0.81 | CYSLTR2 (0.47) | RECQLHTTCSNK1EALDH1A1CYSLTR2 | |
| SCHEMBL22358954 | 0.81 | CYSLTR2 (0.47) | RECQLHTTCSNK1EALDH1A1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115023-B2 | Benzo lipoxin analogues | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100152290-A1 | Benzo Lipoxin Analogues | UNIVERSITY OF SOUTHERN CALIFORNIA | 2010-06-17 | — | — | US | disclosed |
| US-7683193-B2 | Inflammation, autoimmune disease and abnormal cell proliferation; analogs of 15-epi-lipoxin A4; e.g. (5S,6R,E)-methyl 5,6-dihydroxy-8-(2-(1-hydroxyhexyl)phenyl)oct-7-enoate | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152290-A1 | Benzo Lipoxin Analogues | ALOX15B, ALOX12, ALOX15 | RECQL 1089/4885HTT 2086/4885TSHR 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.