SCHEMBL10691446

SCHEMBL10691446

CN(C)c1ccc(C(=O)c2ccc(Cl)cc2)c(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.57
LTC4S Q16873 12/20 0.55
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
MAPT P10636 2/20 0.50
NPC1 O15118 2/20 0.50
MEN1 O00255 1/20 0.50
TP53 P04637 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
POLB P06746 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SRD5A2 P31213 2/20 0.49
RAB9A P51151 1/20 0.47
CDC25A P30304 1/20 0.46
CDC25B P30305 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313297 0.94 NR4A1 (0.57) NR4A1LTC4SALDH1A1HPGDMAPT
SCHEMBL9253503 0.91 MAPT (0.60) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL31119630 0.91 MAPT (0.60) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL18492956 0.89 MAPT (0.58) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL10605623 0.86 AKR1C3 (0.58) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL9218197 0.86 HPGD (0.61) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL11648215 0.84 MAPT (0.60) ALDH1A1HPGDMAPTNPC1MEN1
SCHEMBL17212657 0.84 MAPT (0.49) LTC4SALDH1A1HPGDMAPTNPC1
SCHEMBL2743147 0.83 LTC4S (0.56) NR4A1LTC4S
SCHEMBL9197277 0.82 MEN1 (0.52) LTC4SALDH1A1HPGDMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed