Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694777 | 1.00 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10691733 | 1.00 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10692810 | 0.99 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10693673 | 0.95 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9347849 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10692467 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10690195 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9351433 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9436296 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10692843 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4776973-A | LIQUID CRYSTAL ELECTROOPTICS DISPLAY DEVICE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-10-11 | — | — | US | disclosed |
| EP-0199004-A1 | Pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1986-10-29 | — | — | EP | disclosed |