SCHEMBL10691514

SCHEMBL10691514

CC(C#N)(CF)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CCR1 P32246 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
CYP19A1 P11511 5/20 0.35
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34
HRH1 P35367 1/20 0.34
HTR2B P41595 1/20 0.34
CHRNA4 P43681 1/20 0.34
SLC6A3 Q01959 1/20 0.34
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
AR P10275 1/20 0.33
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1626918 0.82 ESR1 (0.44) ESR1ESR2MEN1KMT2ACCR1
SCHEMBL10193733 0.81 ESR1 (0.43) ESR1ESR2MEN1KMT2ACCR1
SCHEMBL10688902 0.81 ESR1 (0.47) ESR1ESR2MEN1KMT2ACCR1
SCHEMBL10692824 0.76 CYP19A1 (0.37) MEN1KMT2ACCR1NPSR1CYP19A1
SCHEMBL27671400 0.75 KMT2A (0.48) MEN1KMT2ANPSR1CYP19A1SLC6A2
SCHEMBL3413029 0.73 MEN1 (0.50) ESR1ESR2MEN1KMT2ANPSR1
SCHEMBL8445728 0.72 CCR1 (0.43) ESR1ESR2MEN1KMT2ACCR1
SCHEMBL11477882 0.72 ESR1 (0.40) ESR1ESR2MEN1KMT2ACCR1
SCHEMBL10213082 0.70 KMT2A (0.54) MEN1KMT2ACYP19A1POLB
SCHEMBL7863860 0.69 KMT2A (0.58) MEN1KMT2ANPSR1CYP19A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261073-A2 Insecticidal and acaricidal alkane and alkoxy alkane derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1988-03-23 EP disclosed
CN-87105707-A Desinsection and the alkane and the alkoxy derivatives alkane that kill mite 1988-03-09 CN disclosed