Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694013 | 0.93 | PPARD (0.47) | MAOBPPARDALDH1A1CYP3A4HPGD | |
| SCHEMBL10691499 | 0.91 | MAOB (0.51) | MAOBPPARD | |
| SCHEMBL10693512 | 0.83 | PPARD (0.52) | MAOBPPARDALDH1A1CYP3A4HPGD | |
| SCHEMBL10693027 | 0.80 | PPARD (0.49) | MAOBPPARDALDH1A1CYP3A4HPGD | |
| SCHEMBL10691238 | 0.76 | CYSLTR2 (0.57) | PPARD | |
| SCHEMBL10687936 | 0.76 | PPARD (0.71) | MAOBPPARD | |
| SCHEMBL21052036 | 0.75 | PPARD (0.74) | MAOBPPARDALDH1A1CYP3A4HPGD | |
| SCHEMBL9774479 | 0.75 | MAOB (0.58) | MAOBPPARDALDH1A1CYP3A4HPGD | |
| SCHEMBL7907683 | 0.73 | MAOB (0.56) | MAOB | |
| SCHEMBL7907678 | 0.73 | MAOB (0.56) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769482-A | Cyano and thiocyano intermediates | ELI LILLY AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0108592-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4661505-A | 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0108592-A1 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |