Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691549 | 0.93 | MAOB (0.51) | PPARDMAOBALDH1A1CYP3A4HPGD | |
| SCHEMBL10691499 | 0.89 | MAOB (0.51) | PPARDMAOB | |
| SCHEMBL10693512 | 0.79 | PPARD (0.52) | PPARDMAOBALDH1A1CYP3A4HPGD | |
| SCHEMBL10692952 | 0.78 | CYSLTR2 (0.53) | PPARDMAPTCYP2C9 | |
| SCHEMBL10693027 | 0.76 | PPARD (0.49) | PPARDMAOBALDH1A1CYP3A4HPGD | |
| SCHEMBL10687936 | 0.72 | PPARD (0.71) | PPARDMAOB | |
| SCHEMBL21052036 | 0.72 | PPARD (0.74) | PPARDMAOBALDH1A1CYP3A4HPGD | |
| SCHEMBL10691238 | 0.70 | CYSLTR2 (0.57) | PPARDMAPTCYP2C9 | |
| SCHEMBL4216869 | 0.69 | ACMSD (0.72) | MAOBALDH1A1MAPTCYP3A4HPGD | |
| SCHEMBL9774479 | 0.69 | MAOB (0.58) | PPARDMAOBALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769482-A | Cyano and thiocyano intermediates | ELI LILLY AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0108592-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4661505-A | 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0108592-A1 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |