SCHEMBL10691598

SCHEMBL10691598

COc1ccc2cc3ccc(C)cc3c(OCCCCCN3C(=O)c4ccccc4C3=O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RAB9A P51151 3/20 0.49
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
HTR1A P08908 3/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693925 0.92 RAB9A (0.51) HPGDNPSR1RAB9AKMT2AMEN1
SCHEMBL10694173 0.85 HPGD (0.51) HPGDNPSR1RAB9AKMT2AMEN1
SCHEMBL10688747 0.84 RAB9A (0.52) RAB9AKMT2AMEN1MAPTLMNA
SCHEMBL10691871 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10692567 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10692842 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10688314 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10695966 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10695466 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2
SCHEMBL10696014 0.79 MAPT (0.52) HPGDNPSR1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792551-A 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents SYNTEX (U.S.A.) INC. (US) 1988-12-20 US disclosed
EP-0132351-A2 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-30 EP disclosed