Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691371 | 0.89 | KDM4E (0.72) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10689195 | 0.88 | KDM4E (0.71) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10694024 | 0.88 | KDM4E (0.71) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10688987 | 0.86 | KDM4E (0.69) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10609344 | 0.81 | KDM4E (0.77) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10609391 | 0.80 | KDM4E (0.80) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10692320 | 0.79 | KDM4E (0.71) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10686204 | 0.79 | KDM4E (0.74) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10712628 | 0.78 | KDM4E (0.76) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 | |
| SCHEMBL10691961 | 0.77 | ADORA2B (0.42) | KDM4ECYP1A2CYP3A4ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |