Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066238 | 0.90 | BTK (0.76) | BTK | |
| SCHEMBL1068917 | 0.86 | BTK (0.96) | BTK | |
| SCHEMBL1070021 | 0.85 | BTK (0.90) | BTK | |
| SCHEMBL1069548 | 0.84 | BTK (0.88) | BTK | |
| SCHEMBL770592 | 0.84 | BTK (0.89) | BTK | |
| SCHEMBL769731 | 0.84 | BTK (1.00) | BTK | |
| SCHEMBL29359902 | 0.84 | BTK (1.00) | BTK | |
| SCHEMBL1066966 | 0.84 | BTK (0.79) | BTK | |
| SCHEMBL769985 | 0.83 | BTK (0.84) | BTK | |
| SCHEMBL1070359 | 0.83 | BTK (0.86) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947835-B2 | Certain substituted amides, method of making, and method of use thereof | CGI PHARMACEUTICALS, INC. (US) | 2011-05-24 | — | — | US | claimed |
| US-7947835-B2 | Certain substituted amides, method of making, and method of use thereof | CGI PHARMACEUTICALS, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-2270200-A2 | Kinase inhibitors, and methods of using and identifying kinase inhibitors | CGI Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |