Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 14/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tibenelast SCHEMBL449748 | 0.82 | STING1 (0.54) | HPGDSTING1ALDH1A1TSHR | |
| SCHEMBL10688443 | 0.81 | STING1 (0.53) | STING1TSHRCLK1HDAC3HDAC4 | |
| Tibenelast SCHEMBL635433 | 0.81 | STING1 (0.53) | HPGDSTING1ALDH1A1TSHR | |
| SCHEMBL10692662 | 0.81 | STING1 (0.50) | STING1TSHRCLK1HDAC3HDAC4 | |
| Tibenelast SCHEMBL10688452 | 0.81 | STING1 (0.53) | HPGDSTING1ALDH1A1TSHR | |
| Tibenelast SCHEMBL635432 | 0.79 | STING1 (0.49) | STING1CLK1HDAC3HDAC4HDAC1 | |
| SCHEMBL10642176 | 0.77 | STING1 (0.60) | STING1 | |
| SCHEMBL10641965 | 0.77 | STING1 (0.60) | STING1 | |
| SCHEMBL10537567 | 0.76 | STING1 (0.49) | HPGDSTING1ALDH1A1TSHRCLK1 | |
| SCHEMBL10534791 | 0.76 | STING1 (0.49) | HPGDSTING1ALDH1A1TSHRCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253650-A2 | Improvements relating to benzothiophene derivatives | ELI LILLY AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |