Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920716 | 0.86 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10921520 | 0.85 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10925330 | 0.85 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10921502 | 0.85 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10811028 | 0.85 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL9621096 | 0.84 | PPARG (0.46) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10690954 | 0.83 | CYSLTR2 (0.87) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL9302516 | 0.83 | CYSLTR2 (0.87) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10695084 | 0.83 | CYSLTR2 (0.87) | CYSLTR2CYSLTR1PPARALMNACYP1A2 | |
| SCHEMBL10690991 | 0.83 | CYSLTR2 (0.87) | CYSLTR2CYSLTR1PPARALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769482-A | Cyano and thiocyano intermediates | ELI LILLY AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0108592-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4661505-A | 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0108592-A1 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |